Nemati F, behnia S, javanshour E, bahrami M. Studying the effect of environmental pH on the phenomenon of gene transcription: multifractal spectrum. lmj 2024; 20 (3 and 4) :5-14
URL:
http://icml.ir/article-1-625-en.html
Abstract: (360 Views)
Objective: The function and behavior of cells depend on gene expression, which is the main life process. However, gene expression models need to account for environmental factors better. This study introduces a new model that incorporates the effect of pH on gene expression regulation and control.
Method: The model was applied to gene expression data. The system was analyzed using the multifractal spectrum, which captures the non-linearity of gene expression.
Results: The analysis revealed that gene expression responds differently to acidic and alkaline pH. It also demonstrated that lower mRNA levels correspond to higher system stability.
Conclusion: The cell's internal and external conditions were used to find the lowest and highest transcription levels.
Educational:
Research |
Subject:
General Received: 2023/12/1 | Accepted: 2024/02/8 | Published: 2024/06/30
Send email to the article author