Volume 8, Issue 2 (laser medicine journal 2011)
lmj 2011, 8(2): 11-19 |
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Nanostructure induction on the surface of polystyrene using ArF Excimer laser for improvement of biocompatibility. lmj 2011; 8 (2) :11-19
URL: http://icml.ir/article-1-226-en.html
URL: http://icml.ir/article-1-226-en.html
Abstract: (14294 Views)
Background: laser irradiation is a promising method for modifying and nano-structuring of the polymer surfaces. These nanostructures induced by laser irradiation can improve biocompatibility of polymers, significantly.
Material and Methods: In this study, surface of polystyrene (PS) films were treated using ArF Excimer laser (wavelength=193 nm) at different number of pulses. The changes were characterized by atomic force microscopy (AFM), attenuated total reflectance Fourier transform infrared (ATR-FTIR), scanning electron microscopy (SEM) and contact angle measurements. L929 cell culture was used to investigate the biocompatibility of treated laser PS.
Results: The data from ATR-FTIR spectra showed the induction process of oxygen-based functional group into laser treated PS surfaces. AFM and SEM observations demonstrated that a specific nanostructure was created on the laser-treated PS surface. Contact angle measurement indicated that water drop contact angle with one pulse laser-treated PS surface decreased and then gradually increased because of further laser pulses. The data from in vitro assays showed the significant cell attachment and growth onto laser treated samples.
Material and Methods: In this study, surface of polystyrene (PS) films were treated using ArF Excimer laser (wavelength=193 nm) at different number of pulses. The changes were characterized by atomic force microscopy (AFM), attenuated total reflectance Fourier transform infrared (ATR-FTIR), scanning electron microscopy (SEM) and contact angle measurements. L929 cell culture was used to investigate the biocompatibility of treated laser PS.
Results: The data from ATR-FTIR spectra showed the induction process of oxygen-based functional group into laser treated PS surfaces. AFM and SEM observations demonstrated that a specific nanostructure was created on the laser-treated PS surface. Contact angle measurement indicated that water drop contact angle with one pulse laser-treated PS surface decreased and then gradually increased because of further laser pulses. The data from in vitro assays showed the significant cell attachment and growth onto laser treated samples.
Keywords: Polystyrene, surface treatment, Excimer laser, Surface properties, Cell attachment, nanostructures
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