Volume 22, Issue 2 (12-2025)
ASWTR 2025, 22(2): 24-41 |
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Haghdoost F, Shams S, Habibi M, Fateh M, Totonchi M. Alginate-based Polymer Systems: New Technologies in Drug Delivery, Antibacterial Properties and Wound Dressings. ASWTR 2025; 22 (2) :24-41
URL: http://icml.ir/article-1-674-en.html
URL: http://icml.ir/article-1-674-en.html
Department of Regenerative Medicine in Wound Healing, Medical Laser Research Centre, Yara Institute, ACECR, Tehran, Iran
Abstract: (20 Views)
Introduction: Alginate-based polymer systems, as one of the new technologies in the field of medicine and pharmacy, play a prominent role in improving the performance of drug delivery, antibacterial properties and wound dressing. Alginate dressings have been introduced as a cornerstone in advanced wound care due to their exceptional biocompatibility, moisture retention and hemostatic properties. Recent innovations in alginate-based wound dressings include multifunctional biomaterials engineered to accelerate healing, reduce the risk of infection and increase patient comfort. This study reviews the latest advances in the technology of extraction/purification methods, properties and different forms of advanced alginate-based polymer systems.
Methods: These advances include the development of bioactive composite formulations, antimicrobial agents such as silver, growth factors and stimuli-responsive components that enable targeted and controlled therapeutic delivery. New approaches such as nanofibrous methods, smart hydrogels and 3D bioprinted structures enhance the functional and mechanical properties of dressings and facilitate sustained drug release and wound monitoring through integrated sensors.
Results: Studies have shown that alginate-based polymer systems can be better candidates for some of the desired biomedical applications.
Conclusions: This studies showed that alginate-based polymer systems such as hydrogels, scaffolds and microspheres are suitable choices for wound healing purposes compared to other reported materials.
Methods: These advances include the development of bioactive composite formulations, antimicrobial agents such as silver, growth factors and stimuli-responsive components that enable targeted and controlled therapeutic delivery. New approaches such as nanofibrous methods, smart hydrogels and 3D bioprinted structures enhance the functional and mechanical properties of dressings and facilitate sustained drug release and wound monitoring through integrated sensors.
Results: Studies have shown that alginate-based polymer systems can be better candidates for some of the desired biomedical applications.
Conclusions: This studies showed that alginate-based polymer systems such as hydrogels, scaffolds and microspheres are suitable choices for wound healing purposes compared to other reported materials.
Keywords: Alginate, Bioactive Agents, Wound Dressing, Controlled Drug Delivery, Advanced Polymer Systems
Educational: Review |
Subject:
General
Received: 2025/09/6 | Accepted: 2025/09/9 | Published: 2025/12/14
Received: 2025/09/6 | Accepted: 2025/09/9 | Published: 2025/12/14
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