en عمومى General پژوهشي Research <div style="text-align: justify;"><strong>Background:</strong> Chronic wounds are associated with substantial psychological burden, including impaired quality of life, difficulties in emotion regulation, repetitive negative thinking, and reduced psychological flexibility. Reinforcement Sensitivity Theory (RST) provides a framework for understanding psychological adaptation and developing targeted psychological interventions. This study evaluated the effectiveness of an RST-based psychoeducational intervention in improving quality of life and psychological outcomes among patients with chronic wounds.<br> <strong>Methods:</strong> A randomized pretest&ndash;posttest controlled study with a wait-list control group was conducted. Forty patients with chronic wounds were recruited using convenience sampling and randomly allocated to either an intervention group or a wait-list control group.<br> <strong>Results:</strong> After adjustment for baseline scores, significant between-group differences were observed across all outcome variables (P < .001). Compared with controls, participants receiving the intervention demonstrated greater cognitive reappraisal (F = 52.429, &eta;p&sup2; = .593), lower expressive suppression (F = 31.722, &eta;p&sup2; = .468), reduced repetitive negative thinking (F = 37.613, &eta;p&sup2; = .504), greater psychological flexibility (F = 29.509, &eta;p&sup2; = .444), and improved wound-related quality of life (F = 20.151, &eta;p&sup2; = .353). All observed effect sizes were large.<br> <strong>Conclusions:</strong> These findings provide preliminary evidence that the RST-based psychoeducational intervention may serve as a feasible adjunct to standard wound care for improving short-term psychological outcomes and quality of life. However, the absence of follow-up assessments limits conclusions about the durability of these effects. Larger multicenter trials with extended follow-up periods are needed to confirm the long-term effectiveness and generalizability of these findings.</div> Reinforcement Sensitivity Theory, Chronic Wounds, Quality of Life, Emotion Regulation, Cognitive Reappraisal, Expressive Suppression 11 25 http://icml.ir/browse.php?a_code=A-10-687-1&slc_lang=en&sid=1 Amir Lalegani laleganiamir1358@gmail.com 1050031947532846005693 1050031947532846005693 Yes Department of Clinical Psychology, Faculty of Psychology and Educational Sciences, Kharazmi University, Tehran, Iran Mohammad Hatami hatami@khu.ac.ir 1050031947532846005694 1050031947532846005694 No Department of Clinical Psychology, Faculty of Psychology and Educational Sciences, Kharazmi University, Tehran, Iran Jafar Hasani hasanimehr57@khu.ac.ir 1050031947532846005695 1050031947532846005695 No Department of Clinical Psychology, Faculty of Psychology and Educational Sciences, Kharazmi University, Tehran, Iran Mahmood Borjali M.borjali@khu.ac.ir 1050031947532846005696 1050031947532846005696 No Department of Clinical Psychology, Faculty of Psychology and Educational Sciences, Kharazmi University, Tehran, Iran