Advances in Skin, Wound and Tissue Repair
Advances in Skin, Wound and Tissue Repair
ASWTR
Medical Sciences
http://icml.ir
105
journal105
1735-3319
10.61882/aswtr
en
jalali
1402
2
1
gregorian
2023
5
1
20
1
online
1
fulltext
fa
چینش سامانه تصویربرداری نوری طیفی مورد استفاده در تلفن همراه هوشمند و کمی سازی ضایعه بافت پوست مدل شده به منظور کاربری بالینی
A Smartphone-Based Spectral Optical Imaging Setup and Quantifying a Skin Lesion Model Towards Clinical Application
عمومى
General
پژوهشي
Research
<div style="text-align: justify;"><span style="line-height:2;"><span style="font-family:Tahoma;"><span style="font-size:14px;"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA"><span style="color:red">اهداف</span></span></b><span lang="AR-SA"><span style="color:red">:</span></span> <span lang="AR-SA">در سالهای اخیر برخی روشهای غیرتهاجمی برای ارزیابی وضعیت مشکلات (بیماری) پوستی و بافتها ایجاد شدهاند. ارزیابی بیماران بعد از لیزر</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">درمانی برای بهبود بیماری</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">های پوستی، بهصورت بصری و براساس تجربه پزشکان انجام میشود. این نوع بررسی غیر خطی بوده و امکان خطای انسانی وجود دارد، لذا استفاده از روش</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">های کمی و ابزاری در کنار ارزیابی بصری وابسته به پزشک، پیشنهاد میشود. این پژوهش با هدف ارائه یک سیستم اپتیکی بر پایه طیف</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سنجی و استفاده از موبایل جهت بررسی تمایز میان بافت سالم و ناسالم به</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">منظور برای پایش و بررسی روند بیماری پوستی طراحی می</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شود.</span><span dir="LTR" style="font-family:IRLotus"></span></span></span><br>
<span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA"><span style="color:red">مواد و روش</span></span><span dir="LTR"><span new="" roman="" times=""><span style="color:red">‎</span></span></span></b><b><span lang="AR-SA"><span style="color:red">ها:</span></span></b> <span lang="AR-SA">در این پژوهش از روش طیف</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سنجی بازتابی پخشی و تصویر</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">برداری بر پایه طیف استفاده شده است. درواقع با استفاده از تحلیل دادههای طیف</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سنجی از یک ضایعه شبیه</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سازی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده عروق خونی بر روی پوست به عنوان کیس مورد مطالعه، یک روش تصویربرداری برپایه طیف</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سنجی ارائه می شود.</span></span></span><br>
<span style="direction:rtl"><span style="unicode-bidi:embed"><span dir="LTR" lang="AR-SA">‎</span><b><span lang="AR-SA"><span style="color:red">یافته</span></span><span lang="FA"><span style="color:red">‎</span></span></b><b><span lang="AR-SA"><span style="color:red">ها:</span></span></b> <span lang="AR-SA">داده</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">های</span> <span lang="AR-SA">طیفی</span> <span lang="AR-SA">از</span> <span lang="AR-SA">پوست</span> <span lang="AR-SA">مورد</span> <span lang="AR-SA">بررسی</span> <span lang="AR-SA">قرار</span> <span lang="AR-SA">گرفت،</span> <span lang="AR-SA">با</span> <span lang="AR-SA">تحلیل</span> <span lang="AR-SA">داده</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">های</span> <span lang="AR-SA">طیفی</span> <span lang="AR-SA">بازتابی</span> <span lang="AR-SA">پخشی،</span> <span lang="AR-SA">تمایز</span> <span lang="AR-SA">میان</span> <span lang="AR-SA">قله</span> <span lang="AR-SA">جذبی</span> <span lang="AR-SA">پوست</span> <span lang="AR-SA">سالم</span> <span lang="AR-SA">و</span> <span lang="AR-SA">پوست</span> <span lang="AR-SA">دارای</span> <span lang="AR-SA">ضایعه</span> <span lang="AR-SA">(شبیه</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سازی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده)</span> <span lang="AR-SA">مشخص</span> <span lang="AR-SA">شد.</span> <span lang="AR-SA">در</span> <span lang="AR-SA">ادامه</span> <span lang="AR-SA">با</span> <span lang="AR-SA">استفاده</span> <span lang="AR-SA">از</span> <span lang="AR-SA">این</span> <span lang="AR-SA">تمایز</span> <span lang="AR-SA">میان</span> <span lang="AR-SA">قله</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">های</span> <span lang="AR-SA">جذب</span> <span lang="AR-SA">در</span> <span lang="AR-SA">طیف</span> <span lang="AR-SA">بازتابی</span> <span lang="AR-SA">پخشی،</span> <span lang="AR-SA">سیستم</span> <span lang="AR-SA">تصویر</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">برداری</span> <span lang="AR-SA">برای</span> <span lang="AR-SA">ثبت</span> <span lang="AR-SA">تصویر</span> <span lang="AR-SA">همزمان</span> <span lang="AR-SA">پوست</span> <span lang="AR-SA">و</span> <span lang="AR-SA">ضایعه</span> <span lang="AR-SA">پیشنهاد</span> <span lang="AR-SA">شد.</span> <span lang="AR-SA">این</span> <span lang="AR-SA">سیستم</span> <span lang="AR-SA">تصویر</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">برداری</span> <span lang="AR-SA">یک</span> <span lang="AR-SA">چیدمان</span> <span lang="AR-SA">اپتیکی</span> <span lang="AR-SA">اولیه</span> <span lang="AR-SA">جهت</span> <span lang="AR-SA">دستیابی</span> <span lang="AR-SA">به</span> <span lang="AR-SA">تصویر</span> <span lang="AR-SA">بدون</span> <span lang="AR-SA">بازتاب</span> <span lang="AR-SA">آینه</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">ای</span> <span lang="AR-SA">و</span> <span lang="AR-SA">همچنین</span> <span lang="AR-SA">حذف</span> <span lang="AR-SA">عوامل</span> <span lang="AR-SA">محیطی</span> <span lang="AR-SA">مانند</span> <span lang="AR-SA">نور</span> <span lang="AR-SA">محیط</span> <span lang="AR-SA">میباشد.</span> <span lang="AR-SA">در</span> <span lang="AR-SA">واقع</span> <span lang="AR-SA">با</span> <span lang="AR-SA">مشخص</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">کردن</span> <span lang="AR-SA">طول</span> <span lang="AR-SA">موج</span> <span lang="AR-SA">شاخص</span> <span lang="AR-SA">از</span> <span lang="AR-SA">تحلیل</span> <span lang="AR-SA">طیف</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سنجی</span> <span lang="AR-SA">باززتابی</span> <span lang="AR-SA">پخشی</span> <span lang="AR-SA">و</span> <span lang="AR-SA">انتخاب</span> <span lang="AR-SA">منبع</span> <span lang="AR-SA">نور</span> <span lang="AR-SA">مطابق</span> <span lang="AR-SA">با</span> <span lang="AR-SA">طول</span> <span lang="AR-SA">موج</span> <span lang="AR-SA">شاخص</span> <span lang="AR-SA">و</span> <span lang="AR-SA">نوردهی</span> <span lang="AR-SA">به</span> <span lang="AR-SA">ضایعه،</span> <span lang="AR-SA">می</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">توان</span> <span lang="AR-SA">تمایز</span> <span lang="AR-SA">بهتری</span> <span lang="AR-SA">از</span> <span lang="AR-SA">آن</span> <span lang="AR-SA">ضایعه</span> <span lang="AR-SA">و</span> <span lang="AR-SA">ناحیه</span> <span lang="AR-SA">سالم</span> <span lang="AR-SA">اطراف</span> <span lang="AR-SA">را</span> <span lang="AR-SA">نشان</span> <span lang="AR-SA">داد.</span> <span lang="AR-SA">همچنین</span> <span lang="AR-SA">در</span> <span lang="AR-SA">این</span> <span lang="AR-SA">سیستم</span> <span lang="AR-SA">از</span> <span lang="AR-SA">دوربین</span> <span lang="AR-SA">موبایل</span> <span lang="AR-SA">به</span> <span lang="AR-SA">عنوان</span> <span lang="AR-SA">دتکتور</span> <span lang="AR-SA">استفاده</span> <span lang="AR-SA">شده</span> <span lang="AR-SA">است.</span></span></span><br>
<span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA"><span style="color:red">نتیجه</span></span><span dir="LTR" lang="AR-SA"><span new="" roman="" times=""><span style="color:red">‎</span></span></span></b><b><span lang="AR-SA"><span style="color:red">گیری:</span></span></b> <span lang="AR-SA">پس از ثبت تصویر از پوست سالم و ضایعه شبیه</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سازی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده روی پوست به ‎صورت همزمان، به پردازش تصویر و کمی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سازی تصویر ثبت</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده که با طول موج شاخص نوردهی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده، به تشخیص و بررسی پوست و ضایعه شبیه</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">سازی</span><span dir="LTR" lang="AR-SA">‎</span><span lang="AR-SA">شده پرداخته شد.</span></span></span><br>
</span></span></span></div>
<div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:2;"><b><i><span new="" roman="" times=""><span style="color:red">Objectives:</span></span></i></b><span new="" roman="" times=""> In recent years, some non-invasive methods have been developed to assess the state of health and disease of the skin and tissues. The evaluation of patients by the doctor in terms of skin complications and recovery after laser treatment is done visually and based on experience. Therefore, it is suggested to use quantitative and instrumental methods along with the visual evaluation dependent on the doctor. This research is designed with the aim of providing an optical system based on spectroscopy and the use of mobile phones to investigate the distinction between healthy and unhealthy tissue in order to monitor and investigate the process of skin disease.</span><br>
<b><i><span new="" roman="" times=""><span style="color:red">Methods & Materials:</span></span></i></b><span new="" roman="" times=""> Diffuse reflection spectrometry and spectrum-based imaging methods have been used in this research. Analysis of spectroscopic data from a skin lesion of blood vessels as a study, a spectroscopic imaging method is presented.</span><br>
<b><i><span new="" roman="" times=""><span style="color:red">Results:</span></span></i></b><span new="" roman="" times=""> spectral data of the skin were analyzed and the difference between the absorption peak of the lesion with healthy skin and the skin with lesion was determined. In the following, using this distinction, the imaging system was proposed based on the results obtained from spectroscopy. This imaging system is a primary optical arrangement to obtain an image without mirror reflection and also to remove environmental factors such as ambient light. In fact, by choosing the index wavelength and lighting the lesion, it is possible to show a better distinction between that lesion and the surrounding healthy area. Also, in this system, a mobile camera is used as a detector.</span><br>
<b><i><span new="" roman="" times=""><span style="color:red">Conclusion:</span></span></i></b><span new="" roman="" times=""> After recording the image of the lesion and the healthy skin around it simultaneously in one image, image processing and quantification can be used to detect and check tissue changes.</span></span></span></span></div>
تصویربرداری طیفی, طیف سنجی بازتابی پخشی, بافت پوست کروموفور, درماسکوپی, کمی سازی
Spectral optical imaging, diffuse reflectance spectroscopy, quantification, modeling, chromophores skin tissue
5
13
http://icml.ir/browse.php?a_code=A-10-559-1&slc_lang=fa&sid=1
Ziba
Heidary
زیبا
حیدری
1050031947532846005087
1050031947532846005087
No
Physics department, Basic Science Faculty, Imam Khomeini International University, Qazvin, Iran
دانشگاه بین المللی امام خمینی(ره) قزوین – ایران
Elaheh
Nahvifard
الهه
نحوی فرد
nahvifard@sci.ikiu.ac.ir
1050031947532846005088
1050031947532846005088
Yes
Physics department, Basic Science Faculty, Imam Khomeini International University, Qazvin, Iran
دانشگاه بین المللی امام خمینی(ره) قزوین – ایران
Afshan
Shirkavand
افشان
شیرکوند
shirkavand@acecr.ac.ir
1050031947532846005089
1050031947532846005089
No
of Biophotonics, Medical Physics, Department of Photodynamic Therapy, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran
فیزیک پزشکی، گروه پژوهشی فتودینامیک- سازمان جهاد دانشگاهی علوم پزشکی تهران- تهران- ایران
Ezeddin
Mohajerani
عزالدین
مهاجرانی
1050031947532846005090
1050031947532846005090
No
professor of Photonics, Photonics Department, Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Iran
پژوهشکده لیزر و پلاسما- دانشگاه شهید بهشتی- تهران- ایران